FROM THE NORTH

Munich – Rosenheim – Kufstein (A 12 Inntal Freeway, obligatory toll) – Innsbruck (A 13 Brenner Freeway, obligatory toll) – Brenner (A 22 Brenner Freeway, obligatory toll) – Bolzano (Exit Bolzano South) – Merano (MEBO-Highway)

Munich – Garmisch – Innsbruck – Brenner (A 22 Brenner Freeway, obligatory toll) – Bolzano (Exit Bolzano South) – Merano (MEBO-Highway)

Alternative:
Brenner – Sterzing – Jaufenpass – Passeier Valley – Merano
Oetztal – Timmelsjoch – Passeier Valley – Merano

FROM THE WEST

Ulm – Kempten – Fuessen – Fernpass – Imst – Landeck – Reschenpass (State Road 40 + 38) – Merano

Bregenz – Feldkirch – Arlberg – Landeck – Reschenpass (State Road 40 + 38) – Merano

St. Moritz – Ofenpass – Münster – Taufers in Muenster – Glurns –  Merano

Zurich – Landquart – Klosters – Vereinatunnel – Zernez – Ofenpass – Muenster – Taufers in Muenster – Glurns – Merano

FROM THE EAST

Lienz – Innichen – Pustertal (State Road 49) – (A 22 Brenner Freeway, obligatory toll) Bolzano – Merano (MEBO-Highway) – Merano.